Mitogen-Activated Protein Kinase Kinases

A dual-specific protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily.

Also Known As:

MEKs; Map Kinase Kinase; Kinase, Map Kinase; MAP-ERK Kinase; MAPKK; Kinase Kinase, Map; Kinase Kinases, MAP; Kinase, MAP-ERK; Kinase, MAPK; Kinase, MAPK-ERK; Kinases, MAP Kinase; Kinases, MAPK; Kinases, MAPK-ERK; MAP ERK Kinase; MAPK ERK Kinase; MAPK ERK Kinases; Mitogen Activated Protein Kinase Kinase; Mitogen Activated Protein Kinase Kinases; MAP Kinase Kinases; MAPK Kinase; MAPK Kinases; MAPK-ERK Kinase; MAPK-ERK Kinases; MAPKKs; MEK; Mitogen-Activated Protein Kinase Kinase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein-Tyrosine Kinases: 7827
        Mitogen-Activated Protein Kinase Kinases: 6921
        Protein Serine-Threonine Kinases: 3707
        Mitogen-Activated Protein Kinase Kinases: 6921
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7827
      - Mitogen-Activated Protein Kinase Kinases: 6921
    - Protein Serine-Threonine Kinases: 3707
      - Mitogen-Activated Protein Kinase Kinases: 6921

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Disease

Drug/Important Bio-Agent (IBA)